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<h1>Creating the next generation of highly detailed human brain models by building on the BigBrain - the first openly accessible, microscopic resolution 3D model of the human brain.</h1>
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<div class="tool-name">Mapping Molecular Patterns In The Brain</div>
<div class="tool-maker"><em>date:</em> April 13 2026</div>
<div class="tool-description">Revisit the 2025 BigBrain Workshop in Germany and watch Hannah Spitzers talk on Mapping Molecular Patterns in the Brain.</div>
<a href="https://www.youtube.com/watch?v=AATrmWl7COc" class="tool-link">Watch on Youtube <i class="fas fa-arrow-right"></i></a>
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<div class="tool-name">DIY BigBrain 3D Print Files</div>
<div class="tool-maker"><em>date:</em> Mar 18 2026</div>
<div class="tool-description">While BigBrain is usually explored on a computer screen, it can also be brought into the physical world using 3D printing. Click on the link to access the files needed for a 3D printer.</div>
<a href="https://fz-juelich.sciebo.de/s/qG4Fc3Dy8K8xPpt" class="tool-link">Download site <i class="fas fa-arrow-right"></i></a>
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<div class="tool-name">Save the date: BigBrain Workshop 2026</div>
<div class="tool-maker"><em>date:</em> Feb 19 2026</div>
<div class="tool-description">We are pleased to announce that the BigBrain Workshop will happen this year in Montreal from October 20 - 22.</div>
<a href="https://go.fzj.de/BigBrainWorkshop2026" class="tool-link">Go to event page <i class="fas fa-arrow-right"></i></a>
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<div class="tool-name">BigBrain anatomy for beginners by Nicola Palomero-Gallagher</div>
<div class="tool-maker"><em>date:</em> Feb 16 2026</div>
<div class="tool-description">Revisit the Winter School 2021 introductory course. The goal of this course is to familiarize scientists with no, or only very little, knowledge about brain anatomy with major brain structures and their functions. </div>
<a href="https://youtu.be/bTNQCJbYDLE" class="tool-link">Go to Youtube <i class="fas fa-arrow-right"></i></a>
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<div class="tool-name">New Paper: AI Creates Virtual Stainings of Brain Tissue</div>
<div class="tool-maker"><em>date:</em> Feb 11 2026</div>
<div class="tool-description">Alexander Oberstraß and the team at FZJ/INM-1 present a new method to visualise the fine structure of the brain without elaborate laboratory procedures. With the help of AI, they can now virtually show how nerve cells are distributed and how they connect with nerve fibres. The study was published in <a href="https://direct.mit.edu/imag/article/doi/10.1162/IMAG.a.1079/134477/From-fibers-to-cells-Fourier-based-registration">Imaging Neuroscience</a>.</div>
<a href="https://www.fz-juelich.de/en/inm/inm-1/news/announcements/ai-creates-virtual-stainings-of-brain-tissue" class="tool-link">Press release <i class="fas fa-arrow-right"></i></a><br>
<a href="https://direct.mit.edu/imag/article/doi/10.1162/IMAG.a.1079/134477/From-fibers-to-cells-Fourier-based-registration" class="tool-link">Paper<i class="fas fa-arrow-right"></i></a>
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<div class="tool-name">BigBrain Workshop Videos 2025</div>
<div class="tool-maker"><em>date: Dec 1, 2025</em></div>
<div class="tool-description">The 9th BigBrain Workshop took place in Berlin, Germany. The conference started with a training day on Oct 27th, and the main events happening on the 28th and 29th. Click below to see the full conference videos.
</div>
<a href="bigbrainworkshop-2025.html" class="tool-link">Read More <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Casey Paquola receives Early Excellence in Science Award</div>
<div class="tool-maker"><em>date: Nov 3, 2025</em></div>
<div class="tool-description">Dr Casey Paquola has been honoured with the Early Excellence in Science Award by the Bayer Foundation.
</div>
<a href="https://www.fz-juelich.de/en/news/archive/announcements/2025/casey-paquola-receives-early-excellence-in-science-award" class="tool-link" target="_blank">read more <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Women in Science Award for Casey Paquola</div>
<div class="tool-maker"><em>date: Sept 19, 2025</em></div>
<div class="tool-description">Congratulations to Casey on receiving the prestigious For Women in Science Award, presented by L’Oréal together with the German UNESCO Commission and the German Humboldt Network.
</div>
<a href="https://www.fz-juelich.de/en/news/archive/press-release/2025/casey-paquola-receives-for-women-in-science-award" class="tool-link" target="_blank">read more <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured Video from 8th BigBrain Workshop 2024</div>
<div class="tool-maker"><em>date: Sept 15, 2025</em></div>
<div class="tool-description">This video features "EEG Simulation through Integration of Structural Connectivity Data and High-Density Surface Meshes in Brain Region-Specific Network Models" by Alejandro Salinas-Medina.
</div>
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<div class="tool-name">HIBALL team at OHBM 2025</div>
<div class="tool-maker"><em>date: July 14, 2025</em></div>
<div class="tool-description">The HIBALL team met at OHBM 2025 in Brisbane and presented the BigBrain together with the Julich Brain Atlas
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<div class="tool-name">Alan Evans appointed to the Order of Canada</div>
<div class="tool-maker"><em>date: July 03, 2025</em></div>
<div class="tool-description">Congratulations to Alan Evans for his appointment to the Order of Canada.
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<a href="https://www.gg.ca/en/order-canada-appointees-june-30-2025" class="tool-link" target="_blank">read more <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-maker"><em>date: May 8, 2025</em></div>
<div class="tool-description">Please visit the BigBrain Project channel on Youtube. There you will find a library of recordings from events as well as demonstrations of the tools.
</div>
<a href="https://www.youtube.com/channel/UCAxNz4exfs6mxagb3Ufq7-w" class="tool-link" target="_blank">go to channel <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">9th BigBrain Workshop</div>
<div class="tool-maker"><em>date: Mar 20, 2025</em></div>
<div class="tool-description">You are cordially invited to attend the 9th BigBrain Workshop, taking place in Berlin, Germany, on October 28 and 29, 2025.<br><br>
Abstract submissions are now open.
</div>
<a href="https://go.fzj.de/BigBrainWorkshop2025" class="tool-link" target="_blank">read more <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured Paper: Integrating brainstem and cortical functional architectures</div>
<div class="tool-maker"><em>date: Jan 31, 2025</em></div>
<div class="tool-description">In this study (“Integrating brainstem and cortical functional architectures”), we sought out to understand the functional interplay between the cortex and brainstem in awake humans.
</div>
<a href="featured-paper-9.html" class="tool-link">read more <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Katrin Amunt's receives honorary doctorate from the University of Maastricht</div>
<div class="tool-maker"><em>date: Jan 31, 2025</em></div>
<div class="tool-description">“Charting the human brain” Katrin Amunts receives honorary doctorate for groundbreaking research
</div>
<a href="https://www.fz-juelich.de/en/news/archive/announcements/2025/katrin-amunts-receives-honorary-doctorate-from-maastricht-university" class="tool-link">read more <i class="fas fa-arrow-right"></i></a><br>
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<h1 class="full-width text-center">About the BigBrain</h1>
<!-- <h2 class="full-width text-center">technical information</h2> -->
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<img src="images/icon-dataset.png">
<p>Full dataset over 1TB</p>
</div>
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<img src="images/icon-resolution.png">
<p>Scans at 20μm resolution</p>
</div>
<div class="icon">
<img src="images/icon-formats.png">
<p>Multiple formats</p>
</div>
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<img src="images/icon-brain.png">
<p>An expanding brain atlas</p>
</div>
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<p>A thriving community</p>
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<h1 class="full-width text-center small-spacer">What People Say About the BigBrain</h1>
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<h1>Why create the BigBrain</h1>
<h2>A message from Dr. Zilles</h2>
<p>the major advantage of the BigBrain for our work is that the image data of the human brain are registered as a 3D volume at very high spatial resolution. Since the human brain is folded, any part of the cortical ribbon may be subjected to the geometrical effects of this folding, i.e. the cortex is obliquely or even tangentially sectioned at various sites in a 2D representation, e.g. in images of single microtome sections. This effect hampers the measurement of any cortical structure which is bound to the 3D columnar architecture of the cortex. In contrast, the BigBrain allows analyses in 3D, and thus has opened the door to many studies which would not be possible in 2D representations.</p>
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<h1>Martha Crago</h1>
<h2>Vice-Principal (Research + Innovation) McGill University</h2>
<p>With HIBALL the partnership between two world-leading research institutions in computational neuroscience will provide an important platform for the scientists to conduct innovative, interdisciplinary, and complementary research in a rich and collaborative setting.</p>
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<h1>Yoshua Bengio</h1>
<h2>Mila Scientific Director, Quebec Artificial Intelligence Institute</h2>
<p>HIBALL assembles a team with world-leading expertise in neuroimaging, artificial intelligence, neuroscience and neuroinformatics, which complements well the team at Mila. The active participation of several PIs with ties to Mila is very exciting, and we anticipate this lab will further expand the collaboration between neuroscience and AI experts in the Montreal ecosystem, leading to cutting-edge discoveries in both fields.</p>
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<h1>Viktor Jirsa</h1>
<h2>Directeur de Recherche, CNRS</h2>
<p>HIBALL can build on a remarkable expertise and international reputation and will lead to high impact contributions in Human Brain Atlasing, Neuroinformatics, and Machine Learning.</p>
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