Integrative analysis: snm3C-seq × Dominguez2020 bulk methylation

[adamklie]

Context

Compare igvf-data/igvf_sc-islet_snm3c with public-data/Dominguez2020_sc-islet_bulk bulk methyl-seq.

Tasks

• Process bulk methylation data to get comparable metrics (previously failed nextflow pipeline)
• Compare methylation patterns globally and at specific loci (promoters of key genes, etc.)

[adamklie]

Dependencies

• Blocked by Reprocess snm3C-seq with new samples #11 (needs reprocessed snm3C-seq data)

[adamklie]

Status Update (2026-04-09)

Blocked on #11. Deferred.