diff --git a/docs/examples/human-classI.html b/docs/examples/human-classI.html new file mode 100644 index 0000000..d5f9f00 --- /dev/null +++ b/docs/examples/human-classI.html @@ -0,0 +1,2710 @@ + + + + + + +MHC-TP 2.0.3 + + + + + + + + + + +
+ + +
+
+

MHC-TP

+ MHC-TP v2.0.3 +
+

Peptide cluster to allotype motif correlation report.

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+ + +
+

Gibbs Cluster and Reference Motif ComparisonsiEach GibbsCluster motif (left) is paired with its best-matching reference allotype motif (right), ranked by Pearson correlation (PCC). Pick a cluster solution from the dropdown, then use the arrows or dots to step through its clusters. Allele names match the reference logo titles.

+

+ Each cluster solution's GibbsCluster motifs paired with the best-matching + reference allotype motif. Use the arrows to step through clusters. +

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+ + +
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+ Results for 1 cluster + · 1 motif +

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+ Results for 2 clusters + · 2 motifs +

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+ Results for 3 clusters + · 3 motifs +

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+ Results for 4 clusters + · 4 motifs +

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+ Results for 5 clusters + · 4 motifs +

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+ Results for 6 clusters + · 5 motifs +

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Top 3 Allotype Matches per ClusteriFor each GibbsCluster motif, the top 3 reference allotypes scoring above the PCC threshold, all interleaved and ranked best first. PCC is the Pearson correlation between the cluster and reference position-weight matrices (1.0 = identical motif). KLD is the GibbsCluster Kullback–Leibler divergence (motif information content). Search by cluster id or allotype.

+

+ Each cluster's 3 best-matching allotypes above the PCC threshold, ranked overall. +

+ +
+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
#ClusterBest HLA/MHCPCCKLD
12of5HLA-B39:124 + 0.893 + 1.842
22of5HLA-B3942 + 0.890 + 1.842
32of5HLA-B39:82 + 0.889 + 1.842
44of6HLA-B39:124 + 0.888 + 1.372
54of6HLA-B39:52 + 0.883 + 1.372
64of6HLA-B3942 + 0.882 + 1.372
72of4HLA-B39:124 + 0.876 + 1.960
82of4HLA-B39:47 + 0.872 + 1.960
92of4HLA-B39:52 + 0.871 + 1.960
101of3HLA-B39:92 + 0.871 + 2.366
111of3HLA-B39:66 + 0.867 + 2.366
122of3HLA-B5309 + 0.867 + 3.771
131of3HLA-B39:69 + 0.863 + 2.366
142of3HLA-B53:40 + 0.859 + 3.771
152of3HLA-B1513 + 0.852 + 3.771
163of4HLA-B44:257 + 0.842 + 1.893
173of4HLA-B44:103 + 0.838 + 1.893
183of4HLA-B44:188 + 0.838 + 1.893
191of6HLA-B44:65 + 0.838 + 1.704
201of6HLA-B44:332 + 0.837 + 1.704
213of5HLA-B44:332 + 0.837 + 1.767
223of5HLA-B44:65 + 0.836 + 1.767
231of6HLA-B4429 + 0.835 + 1.704
243of5HLA-B44:300 + 0.835 + 1.767
251of5HLA-A68:117 + 0.827 + 1.764
261of5HLA-A68:45 + 0.827 + 1.764
271of5HLA-A6829 + 0.815 + 1.764
284of4HLA-B15:418 + 0.806 + 2.540
294of4HLA-B1513 + 0.806 + 2.540
304of4HLA-B1589 + 0.801 + 2.540
315of6HLA-A25:40 + 0.792 + 1.944
325of6HLA-A25:41 + 0.792 + 1.944
335of6HLA-A25:45 + 0.792 + 1.944
346of6HLA-A68:165 + 0.786 + 1.469
356of6HLA-A68:85 + 0.784 + 1.469
366of6HLA-A68:83 + 0.783 + 1.469
372of2HLA-B1589 + 0.777 + 4.446
385of5HLA-A25:51 + 0.776 + 1.996
395of5HLA-A25:53 + 0.776 + 1.996
405of5HLA-A25:57 + 0.776 + 1.996
412of2HLA-B5309 + 0.775 + 4.446
422of2HLA-B15:418 + 0.773 + 4.446
431of2HLA-B3919 + 0.773 + 4.108
441of2HLA-B39:121 + 0.768 + 4.108
451of2HLA-B39:69 + 0.759 + 4.108
461of4HLA-A6807 + 0.747 + 2.447
471of1HLA-A25:31 + 0.745 + 7.577
481of1HLA-A25:32 + 0.745 + 7.577
491of1HLA-A25:34 + 0.745 + 7.577
503of6HLA-C12:183 + 0.745 + 1.015
513of6HLA-C12:90 + 0.736 + 1.015
523of6HLA-C12:213 + 0.731 + 1.015
533of3HLA-A6807 + 0.728 + 2.738
541of4HLA-A68:105 + 0.726 + 2.447
551of4HLA-A6806 + 0.725 + 2.447
563of3HLA-A68:88 + 0.715 + 2.738
573of3HLA-A6817 + 0.712 + 2.738
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Correlation AnalysisiInteractive views of every cluster↔allotype correlation. Drag the PCC threshold to hide weaker matches. The Heatmap colours each pair by PCC; the Network links clusters to their correlated allotypes. The Combined tab stacks both.

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+ + + 0.70 +
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HeatmapiColour encodes the PCC (0–1) for each cluster × allotype pair above the threshold. Darker = stronger match. Hover a cell for exact values.
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NetworkiForce-directed graph: each cluster (large coloured node) links to the allotypes it correlates with; edge width scales with PCC. Drag nodes, scroll to zoom, hover for details.
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+ + + + \ No newline at end of file diff --git a/docs/examples/mouse.html b/docs/examples/mouse.html new file mode 100644 index 0000000..a4722be --- /dev/null +++ b/docs/examples/mouse.html @@ -0,0 +1,1974 @@ + + + + + + +MHC-TP 2.0.3 + + + + + + + + + + +
+ + +
+
+

MHC-TP

+ MHC-TP v2.0.3 +
+

Peptide cluster to allotype motif correlation report.

+
+ + +
+

Gibbs Cluster and Reference Motif ComparisonsiEach GibbsCluster motif (left) is paired with its best-matching reference allotype motif (right), ranked by Pearson correlation (PCC). Pick a cluster solution from the dropdown, then use the arrows or dots to step through its clusters. Allele names match the reference logo titles.

+

+ Each cluster solution's GibbsCluster motifs paired with the best-matching + reference allotype motif. Use the arrows to step through clusters. +

+ +
+ + +
+ +
+
+

+ Results for 1 cluster + · 1 motif +

+ +
+ + + + +
+ +
+
+

+ Results for 2 clusters + · 2 motifs +

+ +
+ + + + +
+ + + + + +
+ +
+ +
+
+

+ Results for 3 clusters + · 3 motifs +

+ +
+ + + + +
+ + + + + + + +
+ +
+ +
+
+

+ Results for 4 clusters + · 2 motifs +

+ +
+ + + + +
+ + + + + +
+ +
+ +
+
+

+ Results for 5 clusters + · 3 motifs +

+ +
+ + + + +
+ + + + + + + +
+ +
+ + +
+ + +
+

Top 3 Allotype Matches per ClusteriFor each GibbsCluster motif, the top 3 reference allotypes scoring above the PCC threshold, all interleaved and ranked best first. PCC is the Pearson correlation between the cluster and reference position-weight matrices (1.0 = identical motif). KLD is the GibbsCluster Kullback–Leibler divergence (motif information content). Search by cluster id or allotype.

+

+ Each cluster's 3 best-matching allotypes above the PCC threshold, ranked overall. +

+ +
+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
#ClusterBest HLA/MHCPCCKLD
11of1H-2-Kb + 0.848 + 11.813
21of2H-2-Db + 0.807 + 3.459
32of2H-2-Kb + 0.804 + 7.510
45of5H-2-Db + 0.802 + 2.152
53of4H-2-Db + 0.774 + 2.214
63of3H-2-Db + 0.769 + 2.415
71of1H-2-Db + 0.761 + 11.813
81of1H-2-Dd + 0.754 + 11.813
94of5H-2-Kb + 0.746 + 4.976
101of5H-2-Kb + 0.739 + 2.161
112of3H-2-Kb + 0.723 + 4.988
121of3H-2-Kb + 0.716 + 3.098
132of4H-2-Kb + 0.710 + 4.204
+
+
+
+ + +
+

Correlation AnalysisiInteractive views of every cluster↔allotype correlation. Drag the PCC threshold to hide weaker matches. The Heatmap colours each pair by PCC; the Network links clusters to their correlated allotypes. The Combined tab stacks both.

+ +
+ + + 0.70 +
+ +
+ + + + +
+ + + +
+ +
+
+
+
HeatmapiColour encodes the PCC (0–1) for each cluster × allotype pair above the threshold. Darker = stronger match. Hover a cell for exact values.
+
+
+
+
NetworkiForce-directed graph: each cluster (large coloured node) links to the allotypes it correlates with; edge width scales with PCC. Drag nodes, scroll to zoom, hover for details.
+
+
+
+
+ +
+
+
+
+
+ +
+
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+
+
+
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+ + +
+ + + + \ No newline at end of file diff --git a/mkdocs.yml b/mkdocs.yml index 084ee6e..f8c5514 100644 --- a/mkdocs.yml +++ b/mkdocs.yml @@ -34,7 +34,11 @@ nav: - Usage: usage.md - API reference: api.md - LLM guide: llm.md - - Example report: example-report.html + - Example reports: + - Human (class I + II): example-report.html + - Human — class I: examples/human-classI.html + # - Human — class II: examples/human-classII.html # add when a class II dataset is available + - Mouse: examples/mouse.html plugins: - search