I haven't checked where and why this may be happening, but some interactions between RBig and IBig/UBig result in zero denominators, causing some further operations to panic. For example:
>> rbig!(10) / ibig!(10)
1 / 0
>> rbig!(10) / ubig!(10)
1 / 0
>> Rational::from((Rational::simplest_from_f64(123.456).unwrap() * ibig!(10)).round()) / ibig!(10)
247 / 0
This doesn't happen with Relaxed, which leads me to assume it's something to do with the simplification. Tested with dashu 0.4.2 from crates.io.