diff --git a/.github/workflows/unit_tests-aarch64-darwin.yaml b/.github/workflows/unit_tests-aarch64-darwin.yaml
index 892292c..4f37359 100644
--- a/.github/workflows/unit_tests-aarch64-darwin.yaml
+++ b/.github/workflows/unit_tests-aarch64-darwin.yaml
@@ -6,6 +6,8 @@ jobs:
     if: github.event_name == 'pull_request'
     name: Build & Test
     runs-on: macos-latest
+    env:
+      PREFIX: /opt/homebrew
     steps:
       - name: Code checkout
         uses: actions/checkout@v2
diff --git a/Makefile b/Makefile
index 6bcd65d..3d2e049 100644
--- a/Makefile
+++ b/Makefile
@@ -1,10 +1,10 @@
 OS = $(shell uname -s)
 KRUNKIT_RELEASE = target/release/krunkit
 KRUNKIT_DEBUG = target/debug/krunkit
+LIBKRUN = libkrun.1.dylib
 
-ifeq ($(PREFIX),)
-    PREFIX := /usr/local
-endif
+PREFIX ?= /usr/local
+export PREFIX
 
 .PHONY: install clean $(KRUNKIT_RELEASE) $(KRUNKIT_DEBUG)
 
@@ -15,6 +15,7 @@ debug: $(KRUNKIT_DEBUG)
 $(KRUNKIT_RELEASE):
 	cargo build --release
 ifeq ($(OS),Darwin)
+	install_name_tool -change $(LIBKRUN) $(PREFIX)/lib/$(LIBKRUN) $@
 	codesign --entitlements krunkit.entitlements --force -s - $@
 endif
 
diff --git a/README.md b/README.md
index 002c072..4b3a36d 100644
--- a/README.md
+++ b/README.md
@@ -15,13 +15,18 @@ $ brew install krunkit
 
 As noted above, `krunkit` relies on the `efi` flavor of `libkrun`. Ensure that is installed on your system.
 
+Build and install using default `PREFIX` (`/usr/local`):
+
+```
+make
+sudo make install
 ```
-# If libkrun-efi.dylib is not located at /opt/homebrew/opt/libkrun-efi/lib/
-# provide the path at which it's located using the LIBKRUN_EFI variable. Otherwise,
-# the Makefile will default to using the /opt/homebrew/... path.
-$ make LIBKRUN_EFI=<path to libkrun-efi.dylib>
 
-$ sudo make install
+To build with `libkrun-efi` from *Homebrew* or *MacPorts* use the appropriate `PREFIX`:
+
+```
+make PREFIX=/opt/homebrew
+sudo make install PREFIX=/opt/homebrew
 ```
 
 ## Usage
diff --git a/build.rs b/build.rs
index 82f5b90..73247a9 100644
--- a/build.rs
+++ b/build.rs
@@ -3,9 +3,12 @@
 fn main() {
     #[cfg(target_os = "macos")]
     {
-        match std::env::var_os("LIBKRUN_EFI") {
-            Some(path) => println!("cargo:rustc-link-search={}", path.into_string().unwrap()),
-            None => println!("cargo:rustc-link-search=/opt/homebrew/lib"),
-        }
+        // Must match the default PREFIX in the Makefile.
+        const DEFAULT_PREFIX: &str = "/usr/local";
+
+        let prefix = std::env::var("PREFIX").unwrap_or(DEFAULT_PREFIX.to_string());
+        println!("cargo:rustc-link-search={prefix}/lib");
+
+        println!("cargo:rerun-if-env-changed=PREFIX");
     }
 }