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Rather than surface level handling heart rate it now models your blood pressure, calculated based on
(heart rate) * (heart strength) * (vessel status)Where heart rate is variable based on
Heart strength is variable based on
and vessel status is based on
This allows us to model side effects like dizziness, confusion, etc. more naturally than arbitrary sticking it in 100 places
(For example, most immediate negative effects of pain have been moved to effects of high blood pressure)
Rather than repeating the same pattern of "this causes xyz" we can just say "this effect raises blood pressure" which will likely cause the aforementioned effects. Which I think is super duper coo, and feels more natural, and even has cool sandbox side effects like being able to take vasodilators to counter certain negative effects