MashtreeWebX

Browser-based phylogenetic tree builder from Mash MinHash distances — no server required.

MashtreeWebX is a WebAssembly implementation of mashtree by Lee Katz. Upload genome assemblies in FASTA format and get a neighbour-joining tree from Mash distances in seconds, with bootstrap or jackknife support values — all processing in-browser.

Features

• Neighbour-joining tree from pairwise Mash distances
• Bootstrap and jackknife support values
• Configurable k-mer length, sketch size, and hash seed
• Interactive tree visualisation with Newick export
• Scales to dozens of genomes in the browser
• All processing in-browser — no upload, no server

Tech Stack

• Mash — MinHash distance estimation (via Aioli/biowasm WebAssembly)
• patristic — neighbour-joining tree inference (JavaScript, CDC)
• React + Vite — frontend framework
• Cloudflare Pages — global CDN hosting

Getting Started

npm install
npm run dev

Open http://localhost:5173

Running Tests

npm test           # unit tests
npm run test:e2e   # end-to-end tests (requires build first)

Contributing

Contributions welcome. Please open an issue first to discuss changes.

License

GPL-3.0-only — see LICENSE