MTDE Data Elements Updated

• Renamed the field to treatment.complete_resection_clear_margins
• Removed tumor_grade and moved its values and description into the cancer_grade description
• Added case.days_to_sample_collection.
• Renamed index_date to index_event
• Updated tobacco exposure values to use clear string values instead of numeric ranges (1–7)
• Changed gender to sex.
• Fixed some descriptions and spelling mistakes (Prometheus)

Link from analyte to bio specimen

created a link from analyte to bio specimen as the analytical sites combine the aliquots to generate one result on the bio specimen level

Changes for CSF

Added new elements into DD for CSF

Changes for Prometheus v2

More Fields for Prometheus for 3a

Changes for Prometheus

New fields added for the Prometheus project, more information is provided here

Added 'ctDNA' to experimental_strategy of submitted_unaligned_reads node.

Non-breaking changes:
Added 'ctDNA' to experimental_strategy of submitted_unaligned_reads node.

v0.8.5: Fixed a typo in library_strategy: RNA Depletion to rRNA Depletion

fixed typo. No data currently use "RNA Depletion", so changed to "rRNA Depletion", which shouldn't invalidate any current data.

v0.8.4: Added NovaSeq 6000 to read_group instrument_model enum.

Added NovaSeq 6000 to read_group instrument_model enum.
No breaking changes.

v0.8.3: Added disease type for Freenome submission.

Advanced Adenoma added to biospecimen node disease_type property for Freenome submission.

v0.8.2: Removed days_to_diagnosis from required.

Merge pull request #110 from occ-data/diagnosis

removed days_to_diagnosis from required